S-Adenosyl
S-Adenosyl
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S-Adenosyl
Many people use the supplement S-Adenosyl, commonly known as SAMe, and swear by the results. Now pets can benefit form this natural supplement too. SAMe is a detoxifier and antioxidant with many properties that help dogs and cats.
- Supports healthy liver function
- Relieves pain and swelling due to osteoarthritis
- Improves cognitive function
- Snap Tabs variation provides four equal parts for a wide range of weights.
SAMe is best known for improving liver function and metabolic activity in dogs and cats. But this powerful supplement containing milk thistle does much more. SAMe helps treat cognitive disorders, depression, and hepatitis. It’s also effective in treating osteoarthritis by reducing inflammation and helping to regenerate joint tissue.
What you should know about S-Adenosyl:
- Talk to your veterinarian before using this product.
- Follow dosing directions exactly - don’t give your pet more medication than directed and don’t skip doses.
- Read the label carefully for information about storage, possible side effects, and drug interactions.
For additional information about S-Adenosyl, click the “More Information” and “Package Insert” tabs above.
Review Summary
20 total reviews
Rated 4.75 out of 5 stars
100% of respondents would recommend this to a friend
Ratings Distribution
18 5 star reviews
1 4 star reviews
0 3 star reviews
0 2 star reviews
1 1 star reviews
Most Liked Positive Review
w/ diet, a dramatic drop in elevated liver enzymes
I don't know whether I can credit SAMe-425 alone for the improvement (I also began supplementing my dog's diet with dandelion smoothies and kefir, increased her dose of vitamin E and fish oil, and broke up her home-cooked diet to 5 small meals per day), but after 3 months of the combined regimen, my 8-year-old blue heeler's liver enzymes went from off-the-charts high to high normal. Now, 5 months later, the values are completely within normal - about a 300% drop from when she was first diagnosed with advanced hepatobiliary disease. Her doctor said that she'd never seen anything like this. Again, I made several dietary changes at the same time she started taking SAMe-425, so I can't say this medication alone is responsible for the dramatic improvement. Still, much credit has to be given to SAMe-425, since previously a healthy, organic, home-cooked diet had not offset her serious liver problems. I definitely recommend it.
Most Liked Negative Review
Best Quality
I have been purchasing s-adenosyl-100 for my dog and found that I can purchase 60days
worth of these pills for the same price my vet charges me for 30 days.
Reviews
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S-Adenosyl(SAMe)
From Secaucus, NJ, USAComments about S-AdenosylMy dachshund has a history of having high liver enzymes (app. over 1400 in early 2014).now in Dec. 2014 her enzymes dropped to over 600. Also, she was diagnosed with Cushing's Disease which keeps her level of enzymes high - S-Adenosyl(SAMe) helps keep the level down. Really Helpful! -
Works Great!
From Billings MtComments about S-AdenosylMy minature schnauzer has been on this for years. Her liver does not process animal protein. She has enjoyed good health being a vegan and taking s-andesol. -
SAMe S-Adenosyl
From Virginia, USAComments about S-AdenosylMy little dog was having liver problems and was very sick. I took her to the vet and she was prescribed this she has to take a small dose each day and is greatly improved. -
Quick and easy!
From Southbury, CT, USAComments about S-AdenosylI chose to buy the item from here instead of my Vet. Same product, lower price! Easy ordering and it even comes with a cute little dog treat too! -
SamE
From Mpls, MN, USAComments about S-AdenosylI'm so glad I discovered this website the prices are so much more reasonable than what I was paying at my vets. This supplement is being given for liver support and it in addition to changing her diet has normalized her liver values. Going on a year now with no recurrences and normal liver function test results, -
w/ diet, a dramatic drop in elevated liver enzymes
From Santa Fe, NMComments about S-AdenosylI don't know whether I can credit SAMe-425 alone for the improvement (I also began supplementing my dog's diet with dandelion smoothies and kefir, increased her dose of vitamin E and fish oil, and broke up her home-cooked diet to 5 small meals per day), but after 3 months of the combined regimen, my 8-year-old blue heeler's liver enzymes went from off-the-charts high to high normal. Now, 5 months later, the values are completely within normal - about a 300% drop from when she was first diagnosed with advanced hepatobiliary disease. Her doctor said that she'd never seen anything like this. Again, I made several dietary changes at the same time she started taking SAMe-425, so I can't say this medication alone is responsible for the dramatic improvement. Still, much credit has to be given to SAMe-425, since previously a healthy, organic, home-cooked diet had not offset her serious liver problems. I definitely recommend it. -
Great product, great price, reliable shipping!
From UndisclosedComments about S-AdenosylMy dog has been taking these for some time. Her liver levels were high and we have seen them go down since being on this product. I want to keep my loved little dog healthy and happy for as long as I can... this product is helping do it. -
Best Quality
From Hilliard, OH, USAComments about S-AdenosylI have been purchasing s-adenosyl-100 for my dog and found that I can purchase 60days worth of these pills for the same price my vet charges me for 30 days. -
Great Product
From Billings, MT, USAComments about S-AdenosylMy dog has been on it for years. Her liver doesn't function properly. I think it has been a great product for her, as she was not given a much of a chance living. She eats vegetables and takes her pill everyday and enjoys good health! -
Fast Delivery
From Rio Rancho, NM, USAComments about S-AdenosylI buy this for my 13 yr old Collie who takes it twice a day along with several other medications. She takes it to protect her liver and all of her test results done every three months come back great! My vet charges almost triple for this medication. Love the service and the quality of the product.
Displaying Reviews 11 - 20
Q & A
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I cant get this big pill down my dogs throat she has trachyea prblems can i crush and mix it in her food? If i heat it in liquid does it damage the effectivness??
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According to the manufacturer, S-Adenosyl tablets are sensitive to moisture and heat and should not be split or crumbled.
Verified Answer
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The directions said do not crush but I can not get the pill down my small dog. How much of the effect of this pill is loss if I crush it to give to her? This also has milk thissle in it?
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According to the manufacturer, Adenosyl tablets are sensitive to moisture and heat and should not be split or crumbled because they may lose some or all of their effect. We recommend talking with your veterinarian if this product is difficult to administer to your pet. They may be able to suggest a different formula or demonstrate a different technique for easier administration.
Verified Answer
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I am giving my dog S-adenosyl-425. Vet says to wait 1 hour after giving the pill to feed the Dog. If I want to give the pill after he eats how long do I need to wait??
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Per manufacturer, tablets should be given on an empty stomach, at least one hour before meals. Tablets are sensitive to moisture and heat and should not be split or crumbled. The manufacturer doesn't state how long to wait after the pet's meal to administer. This time frame may be 2 to 4 hours depending on the pet and size of meal. Please consult with your veterinarian to determine the appropriate dosing times for your dog.
Verified Answer
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can you soak the S adenosyl tablets so they get soft?
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S-Adenosyl is used in pets to support healthy liver function. The manufacturer states these tablets are enteric-coated, they should not be broken or split and are sensitive to air and moisture. S-Adenosyl tablets should not be soaked. Getting them wet can disrupt the integrity of the medication and your pet may not get the full effect. The coating is designed to dissolve and release the drug at a certain point in the GI tract. They should be taken on an empty stomach at least one hour before or two hours after feeding to increase absorption. Talk with your veterinarian if you have questions about techniques for giving your pet oral medications. Thank you, VetRxDirect
Verified Answer
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does S-Adenosyl-100 come in liquid form?
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S-Adenosyl is not available in a liquid form. We will keep an eye out for SAMe liquid and add it to our site if it becomes available.
Community Answer
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My dog is being treated for dementia. Sam-e with milk thistle 1 tab daily. Dog is small can't hide pill in food anymore. Does it come in liquid form.?
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Yes, this does come in a liquid form, we do not carry it however. We just have the pill form. Thank you, VetRxDirect
Community Answer
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Is milk thistle the same as Sam E? I ntoiced it was more affordable? My dog has high liver enzymes.?
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Although both are used as supplements in liver dysfunction, S-adenosylmethionine (SAMe) is not the same as milk thistle. SAMe is a molecule naturally made in the body, which helps in brain, liver, and other tissue function. Supplemental SAMe is thought to increase liver cell function in animals with decreased liver function. Milk thistle (silymarin) is thought to improve liver function by acting as an anti-oxidant and anti-inflammatory agent, protecting the liver cells from toxins as well as increasing the amount of protein liver cells made. Milk thistle is commonly listed in products as Silybin A and B, which are extracts of silymarin. SAMe and milk thistle can be used together or alone. It would be important to discuss with your pet’s veterinarian in order to select the safest and most appropriate supplement for your pet. Thank you, VetRxDirect
Community Answer
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i've do a research and i've found an article said not to give milk with SAMe for cat . Why??
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There is not an apparent drug-food interaction with SAMe and milk. However, SAMe should be given on an empty stomach, at least one hour before feeding your cat, because food and other products, such as milk, may decrease the effectiveness of SAMe. This is because they may decrease the absorption of SAMe in the GI tract. You should be able to feed your cat milk after an hour of giving SAMe. Thank you, VetRxDirect
Community Answer
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Is there a comparable liquid milk thistle extract for my dog. Many challenges to administering s-a caps and I'm an expert at med disguises. Good results with the product when successfully ingested.?
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We are not aware of any liquid options for the milk thistle or SAMe supplements. You may want to check in with your dog's veterinarian on additional administration options or other supplements that may be easier to administer. Thank you, VetRxDirect
Community Answer
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are these the non chewable pills??
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We carry both forms of the S-Adenosyl supplement, the non-chewable tablets and the chewable. If you are looking for chewable tablets, they are available in one strength, the 225, and are listed as snap tabs, which break apart to allow for dosing at strengths other than 225. The non-chewable come in three strengths, 100, 225, and 425. Thank you, VetRxDirect
Community Answer
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Displaying Questions 1 - 10