Trifexis Rx
Starting At $119.69

Trifexis Rx


$119.69
Or save an extra 5% (up to $20) with Autoship* $113.71
  • Usually ships the same weekday before 3pm CT with veterinary approval.

  • Requires veterinary authorization.

  • Your pet's veterinarian will provide directions for use.

What are Trifexis Chewable Tablets for Dogs?

  • Trifexis is a prescription heartworm disease preventative that contains Spinosad, an insecticide and Milbemycin Oxime, a parasiticide.
  • It starts killing fleas within 30 minutes and prevents flea reinfestation.
  • Trifexis also treats and controls the infection of three intestinal parasites: roundworms, whipworms, and hookworms.

Why do dogs use Trifexis?

  • Veterinarians prescribe Trifexis to prevent heartworm disease, kill fleas, prevent flea infestations, and kill and control hookworms, whipworms, and roundworms.

What else should I know about Trifexis?

  • One tablet provides one month of protection.
  • Flavored chewable tablet, making it easier to give.
  • Trifexis is for use in dogs and puppies 8 weeks of age or older and 5 pounds of body weight or greater.
  • The American Heartworm Society and most veterinarians recommend an annual heartworm test before prescribing a heartworm preventative for your dog or cat. Dogs with existing heartworm infections can have serious reactions after taking this.
  • Talk with your veterinarian for more information and to find the best tick preventative to complement this product.
  • Trifexis is sold as a prescription drug in a maximum of a 12-month supply per dog per year.
  • To buy the same size for more than one dog, add what you need to the cart. You can split the amount to different dogs in checkout!
  • Contact your local waste management about the safe disposal of Trifexis. It can be very toxic to fish and wildlife.

What problems could my dog have with Trifexis?

  • Keep out of reach of other animals. Overdoses can also be serious. Contact your veterinarian if you suspect an overdose.
  • Contact your veterinarian immediately if you see neurologic signs such as weakness, clumsiness, or if your dog has convulsionsl.

How do you use Trifexis?

  • Trifexis should be given with food. Follow your veterinarian's directions.

What is in Trifexis?

  • There are two active ingredients in Trifexis: Spinosad, an insecticide and Milbemycin Oxime, a parasiticide.

Will I get what I see in the picture?

  • Trifexis is a brand name. You will receive the exact brand that you request.

Is it important for my dog to finish all of the Trifexis?

  • Dogs may use Trifexis for different lengths of time. Please consult your veterinarian if you have any questions.