Simplicef (cefpodoxime proxetil) Rx
Simplicef (cefpodoxime proxetil) Rx
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What are Simplicef Tablets for Cats and Dogs?
- Simplicef is a prescription oral medication for dogs and cats that contains Cefpodoxime Proxetil.
- Cefpodoxime Proxetil is an antibiotic that is in the class of cephalosporins.
Why do cats and dogs use Simplicef?
- Simplicef is commonly used for infections in dogs, specifically for skin and urinary infections.
- Simplicef may also be prescribed for certain tyes of skin infections in cats.
What else should I know about Simplicef?
- Cefpodoxime Proxetil is a cephalosporin antibiotic. Cephalosporin antibiotics has an odor that resembles cat urine. This is normal.
What problems could my dog or cat have with Simplicef?
- Cefpodoxime Proxetil generally does not cause major side effects.
- Cefpodoxime Proxetil can cause diarrhea and vomiting. If your pet has severe diarrhea or vomiting, you should contact your pet's veterinarian.
- If your pet has ever had an allergic reaction to any cephalosporin antibiotic, you should not give them Cefpodoxime Proxetil.
How do you use Simplicef?
- Simplicef can be given with our without food.
What is in Simplicef?
- Simplicef contains the antibiotic Cefpodoxime Proxetil.
- Cefpodoxime Proxetil is a cephalosporin antibiotic.
Will I get what I see in the picture?
- Simplicef is a brand name. You will receive the exact brand that you request.
Is it important for my dog or cat to finish all of the Simplicef?
- Simplicef contains an antibiotic. Resistance is a major concern when using antibiotics. To help avoid resistance, it is important for you to use this for as long as your veterinarian has prescribed, even if you dog or cat is looking and feeling better.
Review Summary
4 total reviews
Rated 5.00 out of 5 stars
0% of respondents would recommend this to a friend
Ratings Distribution
4 5 star reviews
0 4 star reviews
0 3 star reviews
0 2 star reviews
0 1 star reviews
Reviews
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It's a very good product.
From MissouriComments about Simplicef (cefpodoxime proxetil)Works fast. -
release to ship antibiotics may have you waiting
From Chicago, IL, USAComments about Simplicef (cefpodoxime proxetil)Simplicef worked great! Product came as described. The price was good. Some shipping issues though. Sending VetRxDirect your prescription to release and ship the antibiotic may have you waiting longer then you wanted to. Communication between my vet and VetRxDirect had my deathly sick dog "Tank" waiting a couple extra days for the Simplicef. In the end, after the prescription issue was taken care of and VetRxDirect sent my purchase with upgraded shipping. My dog is healthy again, thank you so much VetRxDirect :)-
![release to ship antibiotics may have you waiting]()
Left: Moose, Right: Tank
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Works great on my dog with hot spots!
From Sacramento, CA, USAComments about Simplicef (cefpodoxime proxetil)My 9 year old fur baby suffers hot spots every spring. The vets has prescribed him in the past just about everything, temaril-P, cortisone shots, multiple medicated dips, Malaseb shampoo, derma-vet ointment, simplicef, & some others I can't think of right this moment. But Simplicef along with derma-vet ointment(animax), and malaseb shampoo together seems to help calm the itching and the hot spots goes away. My dog is currently on a 10 day simplicef dose, once a day. It is 6th day, I have given him two baths with Malaseb shampoo within the 6 days and animax ointment directly on the hot spots. I noticed it clearing up within the first day, and as of today he is no longer itching or licking, no scabs, or fresh wounds, and his skin is back to light pink. I have used the malaseb shampoo by itself and that didn't clear up the wounds. I've also used up a 15ml tube derma-vet ointment but the hot spots were so overwhelming, only parts of his body cleared up. I truly think the oral medication Simplicef help tremendously along with the baths and ointment. As his whole body is now clear of hot spots. It may again just be temporary until the medication is gone. I have used vetrxdirect in the past and with comparison of how much the vet charges, I save twice if not three times the $$ ordering from vetrxdirect. I will continue to use them or future orders.-
![Works great on my dog with hot spots!]()
feel better if I get a treat ;)
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Saved me a lot of money!
From VirginiaComments about Simplicef (cefpodoxime proxetil)I am so happy that Vetrxdirect had the generic Simplicef for my dog who needed to on this antibiotic for over a month now....-
![Saved me a lot of money!]()
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Displaying Reviews 1 - 4
Q & A
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Can this be used for teeth infections?
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Simplicef, cefpodoxime, is labeled to treat certain types of skin infections in dogs. It may also be prescribed extra label to treat certain types of urinary tract infections in dogs or skin infections in cats. Please consult with your veterinarian with any further questions regarding the use of this medication for your pet.
Verified Answer
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My dog has suddenly been diagnosed with a heart murmur. Could this medication have any thing to do with this??
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Cefpodoxime proxetil, the active ingredient in Simplicef, has not been associated with heart murmurs as an adverse effect. Please contact your veterinarian with further questions.
Verified Answer
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My vet just prescribed Simplicef 100mg three times daily for 7 days. All the literature states it's to be taken one time daily. My dog Wright's 70 pounds. Is three times a day too much??
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what is the shelflife of this medication? simplicef?
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The shelf life of this product can vary depending on when it was manufactured. VetRxDirect will not ship products that expire before the product will be used based on normal directions for use. If you have further questions or concerns regarding this medication contact your veterinarian.
Verified Answer
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My puppy has been on for 3 days pukes in morning1 time do dogs stay on it even when pukes sometimes ?
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The primary side-effects of Simplicef (cefpodoxime proxetil) may include diarrhea and vomiting. If these side-effects occur often, they can affect your pet’s ability to take or absorb the medication. Especially if the vomiting and diarrhea occur around administration of a dose. Frequent vomiting and diarrhea can also cause dehydration in your pet. Taking this medication with food is usually recommended and may help, but if this side-effect continues, you should report it to your pet’s veterinarian. Your pet’s veterinarian will be able to determine if the therapy is still effective, if a longer duration is needed, if the dose may be too high, and how to best minimize any side-effects in the future. Thank you, VetRxDirect
Community Answer
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Can cefopodxime and bendrayl be given together??
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Songie, There are no drug interactions between cefpodoxime and Benadryl (brand named diphenhydramine) and can be safely given together. Keep in mind that cefpodoxime is an antibiotic and may cause allergic reactions in whomever may be susceptible. If this is the case and reason for the Benadryl administration, we recommend having frequent follow up by your veterinarian. Thank you, VetRxDirect
Community Answer
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Simplicef 100 mg seems to be the only medication that helps our 10 yr old cocker with her skin problems but they start to get bad again after 1-2 weeks of being off simplicef. How safe is this to give all the time and if safe to give daily? Thanks. Buni?
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Buni, This drug, along with the other antibiotics in its class, are generally considered safe in dogs. It would be hard to predict any specific side effects your dog may experience from taking it daily long-term. Keeping up with all of the lab and veterinary appointments will help monitor for any long-term problems. Keeping a close eye on your dog and coordinating with the veterinarian are great ways to prevent a problem from happening with this medication, should one occur. Thank you, VetRxDirect
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Displaying Questions 1 - 7